There is often a need to synthesize evidence from multiple studies when evaluating medical interventions from a clinical or health policy perspective. Meta-analysis is an established statistical method for this synthesis when the evidence consists of several head-to-head comparisons of two treatments. The estimation of the relative effectiveness of two treatments for which no head-to-head evidence is available is known as an indirect comparison. Mixed treatment comparison meta-analysis is a generalization of standard pair-wise meta-analysis that derives estimates of treatment effects from a synthesis of direct and indirect evidence. STATinMED Research can assist with your meta analysis needs, including indirect comparison and mixed treatment comparison meta-analysis.